Title : Dendritic cells, obtained from peripheral blood precursors in the presence of PGE2, promote Th2 responses.

Pub. Date : 1997

PMID : 9286387






2 Functional Relationships(s)
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1 Addition of PGE2 (10(-9) M-10(-6) M) to the cultures performed in the presence of GM-CSF and IL-4 did not alter the morphology nor high levels of expression of class II MHC and co-stimulatory molecules on arising DC, although at concentrations above 10(-8) M, the acquisition of CD1a was selectively prevented. Dinoprostone interleukin 4 Homo sapiens
2 Compared to control DC, PGE2-DC induced development of Th cells secreting elevated amounts of IL-4 and IL-5, from naive precursors. Dinoprostone interleukin 4 Homo sapiens