Title : Relaxation by bradykinin in porcine ciliary artery. Role of nitric oxide and K(+)-channels.

Pub. Date : 1997 Aug

PMID : 9286264






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Endothelium-dependent relaxations to bradykinin (maximal [max], 99% +/- 3%) were strongly inhibited by L-NAME (max, 39% +/- 4%, P < 0.01) and partially by TEA (max, 62% +/- 3%, P < 0.01) or glibenclamide (max, 77% +/- 4%, P < 0.01). Tetraethylammonium kininogen 1 Homo sapiens
2 As only relaxations to bradykinin, but not those mediated by SNP, were inhibited by TEA, this implies that K(+)-channel blockers most likely affect the bradykinin-evoked NO production or release by the endothelium. Tetraethylammonium kininogen 1 Homo sapiens
3 As only relaxations to bradykinin, but not those mediated by SNP, were inhibited by TEA, this implies that K(+)-channel blockers most likely affect the bradykinin-evoked NO production or release by the endothelium. Tetraethylammonium kininogen 1 Homo sapiens