Title : Pertubation of B and T cell development and predisposition to lymphomagenesis in Emu Bmi1 transgenic mice require the Bmi1 RING finger.

Pub. Date : 1997 Aug 18

PMID : 9285685






1 Functional Relationships(s)
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1 Mutational analysis of the Bmi1 protein demonstrated that the conserved N-terminal RING finger and central part of Bmi1 are essential for its oncogenic potential whereas the C-terminal Pro-Ser rich region is not required. Serine Bmi1 polycomb ring finger oncogene Mus musculus