Title : Transcriptional repression of the alpha-subunit gene by androgen receptor occurs independently of DNA binding but requires the DNA-binding and ligand-binding domains of the receptor.

Pub. Date : 1997 Sep

PMID : 9280065






2 Functional Relationships(s)
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Protein Name
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1 Instead, two other elements within the promoter-regulatory region (alpha-basal element and cAMP-regulatory element), which are important for expression of the alpha-subunit gene in gonadotropes, mediate the effects of AR. Cyclic AMP androgen receptor Homo sapiens
2 This suggests that AR inhibits activity of the alpha-subunit promoter by interfering with the transcriptional properties of the proteins that bind to alpha-basal element and the cAMP-regulatory elements. Cyclic AMP androgen receptor Homo sapiens