Title : Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis.

Pub. Date : 1997 Sep

PMID : 9271410






2 Functional Relationships(s)
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1 Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Homo sapiens
2 Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Homo sapiens