Title : Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil.

Pub. Date : 1997 Jun 1

PMID : 9264313






4 Functional Relationships(s)
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1 Differences in pharmacokinetic parameters of alfentanil have previously been associated with the wide distribution of CYP3A4, the only known hepatic cytochrome P450 monooxygenase (CYP) involved in the conversion of alfentanil to noralfentanil. Alfentanil cytochrome P450 family 20 subfamily A member 1 Homo sapiens
2 Differences in pharmacokinetic parameters of alfentanil have previously been associated with the wide distribution of CYP3A4, the only known hepatic cytochrome P450 monooxygenase (CYP) involved in the conversion of alfentanil to noralfentanil. Alfentanil cytochrome P450 family 20 subfamily A member 1 Homo sapiens
3 Differences in pharmacokinetic parameters of alfentanil have previously been associated with the wide distribution of CYP3A4, the only known hepatic cytochrome P450 monooxygenase (CYP) involved in the conversion of alfentanil to noralfentanil. Alfentanil cytochrome P450 family 20 subfamily A member 1 Homo sapiens
4 Differences in pharmacokinetic parameters of alfentanil have previously been associated with the wide distribution of CYP3A4, the only known hepatic cytochrome P450 monooxygenase (CYP) involved in the conversion of alfentanil to noralfentanil. Alfentanil cytochrome P450 family 20 subfamily A member 1 Homo sapiens