Title : The molecular response to reductive stress in LLC-PK1 renal epithelial cells: coordinate transcriptional regulation of gadd153 and grp78 genes by thiols.

Pub. Date : 1997 Mar

PMID : 9250393






3 Functional Relationships(s)
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1 The molecular response to reductive stress in LLC-PK1 renal epithelial cells: coordinate transcriptional regulation of gadd153 and grp78 genes by thiols. Sulfhydryl Compounds heat shock protein family A (Hsp70) member 5 Sus scrofa
2 Treatment of cells with thiols activates expression of grp78, but it is not known if, like other forms of stress, there is a battery of stress response genes that are induced by thiols. Sulfhydryl Compounds heat shock protein family A (Hsp70) member 5 Sus scrofa
3 In LLC-PK1 renal epithelial cells, mRNAs for both grp78 and gadd153 were induced by thiols with similar time, concentration and structure-activity dependence. Sulfhydryl Compounds heat shock protein family A (Hsp70) member 5 Sus scrofa