Title : cAMP induces heme oxygenase-1 gene expression and carbon monoxide production in vascular smooth muscle.

Pub. Date : 1997 Jul

PMID : 9249506






3 Functional Relationships(s)
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1 Treatment of smooth muscle cells with the membrane-permeable cAMP derivative dibutyryl cAMP or with compounds that increase intracellular cAMP levels (isoproterenol and forskolin) resulted in a concentration- and time-dependent increase in the levels of HO-1 mRNA and protein, whereas the expression of HO-2 remained unchanged. dibutyryl cathelicidin antimicrobial peptide Rattus norvegicus
2 Treatment of smooth muscle cells with the membrane-permeable cAMP derivative dibutyryl cAMP or with compounds that increase intracellular cAMP levels (isoproterenol and forskolin) resulted in a concentration- and time-dependent increase in the levels of HO-1 mRNA and protein, whereas the expression of HO-2 remained unchanged. dibutyryl cathelicidin antimicrobial peptide Rattus norvegicus
3 Treatment of smooth muscle cells with the membrane-permeable cAMP derivative dibutyryl cAMP or with compounds that increase intracellular cAMP levels (isoproterenol and forskolin) resulted in a concentration- and time-dependent increase in the levels of HO-1 mRNA and protein, whereas the expression of HO-2 remained unchanged. dibutyryl cathelicidin antimicrobial peptide Rattus norvegicus