Title : Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules.

Pub. Date : 1997 Jun 30

PMID : 9237666






2 Functional Relationships(s)
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1 By screening a rat cDNA library with labelled resiniferatoxin, we unexpectedly isolated a novel rat phosphotriesterase homologue, here named rpr-1, that encodes a 349 amino acid, 39 kDa protein (confirmed by in vitro translation). resiniferatoxin phosphotriesterase related Rattus norvegicus
2 Northern blotting and in situ hybridisation show expression primarily in proximal tubules of the kidney, in which rpr-1 distribution correlates with resiniferatoxin-binding activity. resiniferatoxin phosphotriesterase related Rattus norvegicus