Title : cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.

Pub. Date : 1997 Jul 25

PMID : 9228017






6 Functional Relationships(s)
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1 cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
2 In this paper, we describe the cloning and characterization of the first mammalian retinoic acid-inducible retinoic acid-metabolizing cytochrome P450 (hP450RAI), which belongs to a novel class of cytochromes (CYP26). Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
3 We also show that hP450RAI mRNA expression is highly induced by RA in certain human tumor cell lines and further show that RA-inducible RA metabolism may correlate with P450RAI expression. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
4 We also show that hP450RAI mRNA expression is highly induced by RA in certain human tumor cell lines and further show that RA-inducible RA metabolism may correlate with P450RAI expression. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
5 We also show that hP450RAI mRNA expression is highly induced by RA in certain human tumor cell lines and further show that RA-inducible RA metabolism may correlate with P450RAI expression. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens
6 We also show that hP450RAI mRNA expression is highly induced by RA in certain human tumor cell lines and further show that RA-inducible RA metabolism may correlate with P450RAI expression. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens