Title : Lexipafant inhibits platelet activating factor enhanced neutrophil functions.

Pub. Date : 1997 May

PMID : 9224389






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Platelet activating factor (PAF) enhances polymorphonuclear leukocyte (PMN) superoxide (.O2-) production, CD11b expression, and elastase release, all essential components in the pathophysiology of multiple-organ failure. Superoxides PCNA clamp associated factor Homo sapiens
2 Platelet activating factor (PAF) enhances polymorphonuclear leukocyte (PMN) superoxide (.O2-) production, CD11b expression, and elastase release, all essential components in the pathophysiology of multiple-organ failure. Superoxides PCNA clamp associated factor Homo sapiens
3 Lexipafant attenuated the PAF-mediated upregulation of PMN .O2- production, CD11b expression, and elastase release in a dose dependent fashion. Superoxides PCNA clamp associated factor Homo sapiens