Pub. Date : 1997 Jul
PMID : 9221926
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Haloperidol regulates neurotensin gene expression in striatum of c-fos-deficient mice. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |
| 2 | The immediate-early gene c-fos has been proposed to play a role in induction of neurotensin/neuromedin N (NT/N) gene expression in the striatum following acute haloperidol (HAL) treatment. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |
| 3 | The immediate-early gene c-fos has been proposed to play a role in induction of neurotensin/neuromedin N (NT/N) gene expression in the striatum following acute haloperidol (HAL) treatment. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |
| 4 | A robust increase in NT/N gene expression was observed in the dorsolateral striatum (DLSt) in both wild-type (WT) and c-fos-deficient mice 4-6 h after a single injection of HAL (1 or 4 mg/kg) indicating that products of the c-fos gene are not absolutely required for induction of NT/N mRNA. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |
| 5 | A robust increase in NT/N gene expression was observed in the dorsolateral striatum (DLSt) in both wild-type (WT) and c-fos-deficient mice 4-6 h after a single injection of HAL (1 or 4 mg/kg) indicating that products of the c-fos gene are not absolutely required for induction of NT/N mRNA. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |
| 6 | HAL-induced NT/N mRNA levels were significantly lower in c-fos knockout mice than in WT mice on PD 10 and 15. | Haloperidol | FBJ osteosarcoma oncogene | Mus musculus |