Pub. Date : 1997 Jul
PMID : 9221835
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Net TGF-beta1 production in injured RPTC increased 1.7- and 3.2-fold on Days 1 and 2, respectively, and returned to control levels 4 days following TBHP treatment. | tert-Butylhydroperoxide | transforming growth factor beta 1 | Homo sapiens |
| 2 | An anti-TGF-beta antibody increased monolayer confluence to 50% and DNA content 1.3-fold 4 days after TBHP exposure. | tert-Butylhydroperoxide | transforming growth factor beta 1 | Homo sapiens |
| 3 | The results demonstrate that TBHP-induced injury increases net TGF-beta1 production in RPTC and that autocrine TGF-beta1 inhibits regeneration of the monolayer by potentiating cellular injury and monolayer deterioration. | tert-Butylhydroperoxide | transforming growth factor beta 1 | Homo sapiens |