Title : Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.

Pub. Date : 1997 Jul 11

PMID : 9211849






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Transfection of NP-C fibroblasts with wild-type NPC1 cDNA resulted in correction of their excessive lysosomal storage of LDL cholesterol, thereby defining the critical role of NPC1 in regulation of intracellular cholesterol trafficking. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
2 Transfection of NP-C fibroblasts with wild-type NPC1 cDNA resulted in correction of their excessive lysosomal storage of LDL cholesterol, thereby defining the critical role of NPC1 in regulation of intracellular cholesterol trafficking. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens
3 Transfection of NP-C fibroblasts with wild-type NPC1 cDNA resulted in correction of their excessive lysosomal storage of LDL cholesterol, thereby defining the critical role of NPC1 in regulation of intracellular cholesterol trafficking. Cholesterol NPC intracellular cholesterol transporter 1 Homo sapiens