Title : Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression.

Pub. Date : 1997 Jul 8

PMID : 9207075






1 Functional Relationships(s)
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1 Pulsatile but not continuous GH exposure activates liver STAT5b by tyrosine phosphorylation, leading to dimerization, nuclear translocation, and transcriptional activation of the STAT, which is proposed to play a key role in regulating the sexual dimorphism of liver gene expression induced by pulsatile plasma GH. Tyrosine signal transducer and activator of transcription 5B Mus musculus