Title : Seizure-related changes in the glutamate R2 and R5 receptor genes expression in the rat hippocampal formation.

Pub. Date : 1997

PMID : 9203076






2 Functional Relationships(s)
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1 In the dentate gyrus, resistant to neurodegeneration, pilocarpine and kainate differentially affected the expression of GluR2 and GluR5 mRNAs. Kainic Acid glutamate ionotropic receptor kainate type subunit 1 Rattus norvegicus
2 However, differences in the kainate-and pilocarpine-induced changes in the dentate gyrus at the late time points indicate that alterations in the stoichiometry of GluR2 forms of GluR5 gene expression in this brain region are not a common causal factor responsible for delayed neuronal hyperexcitability. Kainic Acid glutamate ionotropic receptor kainate type subunit 1 Rattus norvegicus