Pub. Date : 1997 Jul 4
PMID : 9202001
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Conditional expression of MKP-1 inhibited PMA-induced ERK2, SAPK, and p38 MAPK activity. | Tetradecanoylphorbol Acetate | dual specificity phosphatase 1 | Homo sapiens |
| 2 | This differential substrate specificity of MKP-1 can be functionally extended to nuclear transcriptional events in that PMA-induced c-Jun transcriptional activity was more sensitive to inhibition by MKP-1 than either Elk-1 or c-Myc. | Tetradecanoylphorbol Acetate | dual specificity phosphatase 1 | Homo sapiens |
| 3 | This differential substrate specificity of MKP-1 can be functionally extended to nuclear transcriptional events in that PMA-induced c-Jun transcriptional activity was more sensitive to inhibition by MKP-1 than either Elk-1 or c-Myc. | Tetradecanoylphorbol Acetate | dual specificity phosphatase 1 | Homo sapiens |
| 4 | Conditional expression of MKP-1 also abolished the induction of endogenous MKP-1 protein expression in response to PMA treatment. | Tetradecanoylphorbol Acetate | dual specificity phosphatase 1 | Homo sapiens |
| 5 | Conditional expression of MKP-1 also abolished the induction of endogenous MKP-1 protein expression in response to PMA treatment. | Tetradecanoylphorbol Acetate | dual specificity phosphatase 1 | Homo sapiens |