Title : CP-96,345, which inhibits [3H] substance P binding, selectively inhibits the behavioral response to intrathecally administered N-methyl-D-aspartate, but not substance P, in the mouse.

Pub. Date : 1997 Jun

PMID : 9190858






1 Functional Relationships(s)
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1 The more potent inhibitor of [3H] SP binding, (+)-(2S,3S)-3-(2-methoxybenzylamino)-2-phenylpiperidine (CP-99,994), was approximately 10 times more potent in inhibiting NMDA-induced activity than CP-96,345. 3-(2-methoxybenzylamino)-2-phenylpiperidine tachykinin 1 Mus musculus