Title : Multidrug resistance-reversing agents increase vinblastine distribution in normal tissues expressing the P-glycoprotein but do not enhance drug penetration in brain and testis.

Pub. Date : 1997 Jun

PMID : 9190857






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The aim of this study was to assess whether P-glycoprotein (Pgp) inhibitors altered the blood-brain barrier and enhanced vinblastine (VBL) distribution in brain, testis and other Pgp-expressing tissues. Vinblastine phosphoglycolate phosphatase Mus musculus
2 The aim of this study was to assess whether P-glycoprotein (Pgp) inhibitors altered the blood-brain barrier and enhanced vinblastine (VBL) distribution in brain, testis and other Pgp-expressing tissues. Vinblastine phosphoglycolate phosphatase Mus musculus