Title : Hepatocellular carcinoma p53 G > T transversions at codon 249: the fingerprint of aflatoxin exposure?

Pub. Date : 1997 Apr

PMID : 9189703






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Hepatocellular carcinoma p53 G > T transversions at codon 249: the fingerprint of aflatoxin exposure? Aflatoxins tumor protein p53 Homo sapiens
2 Patients from areas with high aflatoxin levels were more likely to have p53 mutations than were patients from areas with low aflatoxin levels. Aflatoxins tumor protein p53 Homo sapiens
3 In the group with p53 mutations, patients from areas with high aflatoxin levels had higher proportions of mutations with codon 249 G > T transversions. Aflatoxins tumor protein p53 Homo sapiens
4 Aflatoxin may increase the proportion of p53 mutations by causing a single mutation, the codon 249 G > T transversion, thus explaining some of the excess liver cancer associated with aflatoxin exposure. Aflatoxins tumor protein p53 Homo sapiens
5 Aflatoxin may increase the proportion of p53 mutations by causing a single mutation, the codon 249 G > T transversion, thus explaining some of the excess liver cancer associated with aflatoxin exposure. Aflatoxins tumor protein p53 Homo sapiens