Title : Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.

Pub. Date : 1997 Jun

PMID : 9187658






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The site of action is the de novo folate biosynthesis enzyme dihydropteroate synthase (DHPS) where sulfonamides act as analogues of one of the substrates, para-aminobenzoic acid (pABA). 4-Aminobenzoic Acid Dihydropteroate synthase Escherichia coli
2 The site of action is the de novo folate biosynthesis enzyme dihydropteroate synthase (DHPS) where sulfonamides act as analogues of one of the substrates, para-aminobenzoic acid (pABA). 4-Aminobenzoic Acid Dihydropteroate synthase Escherichia coli