Title : Hexokinase inactivation induced by ascorbic acid/Fe(II) in rabbit erythrocytes is independent of glutathione-reductive processes and appears to be mediated by dehydroascorbic acid.

Pub. Date : 1997 Jun 15

PMID : 9186478






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Hexokinase inactivation induced by ascorbic acid/Fe(II) in rabbit erythrocytes is independent of glutathione-reductive processes and appears to be mediated by dehydroascorbic acid. Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus
2 Our results demonstrate superimposable kinetics of hexokinase decay promoted by either ascorbic acid/Fe(II) or dehydroascorbic acid in erythrocyte lysates in which the reduced glutathione (GSH) levels were variously manipulated. Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus
3 As a consequence, dehydroascorbic acid appears to be the species which directly inhibits hexokinase. Dehydroascorbic Acid hexokinase-2 Oryctolagus cuniculus