Title : The oligosaccharide side chain on Asn-135 of alpha-antithrombin, absent in beta-antithrombin, decreases the heparin affinity of the inhibitor by affecting the heparin-induced conformational change.

Pub. Date : 1997 Jun 3

PMID : 9184148






1 Functional Relationships(s)
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1 These and previous results suggest a model in which the Asn-135 oligosaccharide of alpha-antithrombin is oriented away from the heparin binding site and does not interfere with the first step of heparin binding. asn-135 oligosaccharide serpin family C member 1 Homo sapiens