Title : Effect of interleukin-1 beta, tumour necrosis factor-alpha and interferon-gamma on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells.

Pub. Date : 1997 Jun

PMID : 9179403






1 Functional Relationships(s)
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1 The glucocorticosteroid dexamethasone and protein synthesis inhibitors, cycloheximide and actinomycin D, not only markedly inhibited IL-1 beta-stimulated PGE2 release and COX activity but also suppressed IL-1 beta-induced COX-2 induction. Dactinomycin mitochondrially encoded cytochrome c oxidase II Homo sapiens