Pub. Date : 1997 May
PMID : 9178432
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The liver-type, NADP(+)-dependent 11 beta-HSD-1, has an affinity in the micromolar range and bidirectional activity. | NADP | 11-beta-hydroxysteroid dehydrogenase 1 | Ovis aries |
| 2 | The NADP(+)-dependent activity had a Km for corticosterone of 4 +/- 1.3 nM for a Km for cortisol of 35.2 +/- 2 nM, 100-fold lower than that described for the 11 beta-HSD-1 in the liver of sheep and other species, and was more prevalent in the microsomes than the nuclei. | NADP | 11-beta-hydroxysteroid dehydrogenase 1 | Ovis aries |