Title : Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3.

Pub. Date : 1997 Jun 6

PMID : 9169439






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TS1, the CBD, and an IAP agonist peptide (4N1K) from the CBD of TS1 activate the platelet integrin alphaIIbbeta3, resulting in platelet spreading on immobilized fibrinogen, stimulation of platelet aggregation, and enhanced tyrosine phosphorylation of focal adhesion kinase. Tyrosine CD47 molecule Homo sapiens