Title : Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin.

Pub. Date : 1997 May

PMID : 9163681






1 Functional Relationships(s)
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1 As for cell proliferation biomarkers, dietary exposure of diosmin and hesperidin significantly decreased the 5"-bromodeoxyuridine-labeling index and argyrophilic nuclear organizer region"s number in crypt cells, colonic mucosal ornithine decarboxylase activity, and polyamine levels in the blood. Diosmin ornithine decarboxylase 1 Rattus norvegicus