Title : Twin hydroxymethyluracil-A base pair steps define the binding site for the DNA-binding protein TF1.

Pub. Date : 1997 May 16

PMID : 9148920






1 Functional Relationships(s)
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Protein Name
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1 Replacement of all hmU residues with thymine decreases the affinity of TF1 greatly; remarkably, the high affinity is restored when the two hmU-A base pair steps corresponding to previously suggested sites of distortion are reintroduced into otherwise T-containing DNA. Thymine TF1 Bacillus phage SPO1