Pub. Date : 1997 May 13
PMID : 9144177
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone. | Dihydrotestosterone | N-myc downstream regulated 1 | Homo sapiens |
2 | More importantly, both DDPCR and Northern blot analysis further demonstrated that the expression of TDD5 was differentially repressed by T and dihydrotestosterone (DHT) at the mRNA level. | Dihydrotestosterone | N-myc downstream regulated 1 | Homo sapiens |
3 | Finally, our animal studies further confirm that TDD5 mRNA levels can be repressed to the basal level 8 hr after DHT administration. | Dihydrotestosterone | N-myc downstream regulated 1 | Homo sapiens |
4 | The isolation and characterization of the early-responsive androgen target gene TDD5 and the fact that TDD5 mRNA level can be differentially regulated by T and DHT may provide a useful tool to study the molecular mechanism of androgen preference on target gene regulation. | Dihydrotestosterone | N-myc downstream regulated 1 | Homo sapiens |
5 | The isolation and characterization of the early-responsive androgen target gene TDD5 and the fact that TDD5 mRNA level can be differentially regulated by T and DHT may provide a useful tool to study the molecular mechanism of androgen preference on target gene regulation. | Dihydrotestosterone | N-myc downstream regulated 1 | Homo sapiens |