Title : Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone.

Pub. Date : 1997 May 13

PMID : 9144177






5 Functional Relationships(s)
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1 Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone. Dihydrotestosterone N-myc downstream regulated 1 Homo sapiens
2 More importantly, both DDPCR and Northern blot analysis further demonstrated that the expression of TDD5 was differentially repressed by T and dihydrotestosterone (DHT) at the mRNA level. Dihydrotestosterone N-myc downstream regulated 1 Homo sapiens
3 Finally, our animal studies further confirm that TDD5 mRNA levels can be repressed to the basal level 8 hr after DHT administration. Dihydrotestosterone N-myc downstream regulated 1 Homo sapiens
4 The isolation and characterization of the early-responsive androgen target gene TDD5 and the fact that TDD5 mRNA level can be differentially regulated by T and DHT may provide a useful tool to study the molecular mechanism of androgen preference on target gene regulation. Dihydrotestosterone N-myc downstream regulated 1 Homo sapiens
5 The isolation and characterization of the early-responsive androgen target gene TDD5 and the fact that TDD5 mRNA level can be differentially regulated by T and DHT may provide a useful tool to study the molecular mechanism of androgen preference on target gene regulation. Dihydrotestosterone N-myc downstream regulated 1 Homo sapiens