Pub. Date : 1979 Aug 1
PMID : 91367
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Electrophoresis of S-alpha 2M in the presence of sodium dodecylsulphate gave results consistent with the view that the alpha 2M molecule is a tetramer of identical subunits, assembled as a non-covalent pair of disulphide-linked dimers. | disulphide | alpha-2-macroglobulin | Homo sapiens |
| 2 | Exposure of S-alpha 2M to 3 M-urea or pH3 resulted in dissociation to the disulphide-bonded half-molecules; these did not show the proteinase-binding activity characteristic of the intact alpha 2M. | disulphide | alpha-2-macroglobulin | Homo sapiens |
| 3 | F-alpha 2M formed by reaction with a proteinase or ammonium salts was not dissociated under the same conditions, although the interchain disulphide bonds were reduced. | disulphide | alpha-2-macroglobulin | Homo sapiens |