Pub. Date : 1996 Dec
PMID : 9124843
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate. | Amoxicillin | beta-lactamase TEM-1 | Haemophilus influenzae |
| 2 | A PAE of 0.8 h was found for amoxicillin (four times the MIC) against a beta-lactamase-negative strain of H. influenzae (generation time, 26.3 min) and a PAE of 1.74 h was found for amoxicillin-clavulanate (twice the MIC) against a beta-lactamase-positive strain (generation time, 32.2 min). | Amoxicillin | beta-lactamase TEM-1 | Haemophilus influenzae |
| 3 | The PLIE was related to the amount of beta-lactamase produced and required the presence of amoxicillin in the initial exposure period. | Amoxicillin | beta-lactamase TEM-1 | Haemophilus influenzae |