Title : PACAPs stimulate duodenal bicarbonate secretion at PACAP receptors in the rat.

Pub. Date : 1997 Mar

PMID : 9124587






1 Functional Relationships(s)
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1 The duodenal HCO(3)- stimulatory action of PACAP-27 was potentiated by pretreatment with 3-isobutyl-1-methylxanthine, similar to that of prostaglandin E2, and was significantly attenuated by PACAP-(6--27) (PACAP antagonist) or Ac-Tyr1,D-Phe2-VIP (VIP antagonist) but was not affected by bilateral vagotomy or prior administration of atropine, verapamil, and indomethacin. Verapamil adenylate cyclase activating polypeptide 1 Rattus norvegicus