Title : Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.

Pub. Date : 1997 Apr

PMID : 9113345






1 Functional Relationships(s)
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1 The Eadie-Hofstee plot of DMO N-demethylation was consistent with single-enzyme Michaelis-Menten kinetics (Vmax varying from 3.3 to 6.8 nmol mg-1 min-1, K(m) from 231 to 322 microM). Nitrogen CD59 molecule (CD59 blood group) Homo sapiens