Title : Evidence for CYP2D1-mediated primary and secondary O-dealkylation of ethylmorphine and codeine in rat liver microsomes.

Pub. Date : 1997 Feb 21

PMID : 9105413






2 Functional Relationships(s)
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1 The contribution of CYP2D1 to the O-dealkylation of EM/NEM and CD/NCD was further confirmed by use of the specific CYP2D1 inhibitors quinine and propafenone. Quinine cytochrome P450, family 2, subfamily d, polypeptide 1 Rattus norvegicus
2 The contribution of CYP2D1 to the O-dealkylation of EM/NEM and CD/NCD was further confirmed by use of the specific CYP2D1 inhibitors quinine and propafenone. Quinine cytochrome P450, family 2, subfamily d, polypeptide 1 Rattus norvegicus