Title : Amlodipine and benazeprilat differently affect the responses to endothelin-1 and bradykinin in porcine ciliary arteries: effects of a low and high dose combination.

Pub. Date : 1997 Mar

PMID : 9088736






3 Functional Relationships(s)
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1 Amlodipine and benazeprilat differently affect the responses to endothelin-1 and bradykinin in porcine ciliary arteries: effects of a low and high dose combination. benazeprilat kininogen 1 Homo sapiens
2 On the other hand, benazeprilat enhanced the sensitivity (concentration shift 73-fold; p < 0.05) and maximal relaxation to bradykinin (by 27%; p < 0.01), whereas amlodipine or the low or high dose combination were ineffective. benazeprilat kininogen 1 Homo sapiens
3 In contrast, endothelium-dependent relaxations to bradykinin were enhanced by benazeprilat alone, but not when combined with amlodipine. benazeprilat kininogen 1 Homo sapiens