Title : Protein engineering strategies for designing more stable hemoglobin-based blood substitutes.

Pub. Date : 1997 Jan-Mar

PMID : 9083641






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Large apolar residues (Leu, Phe, Trp) at the B10 and E11 positions inhibit NO-induced and autooxidation in both myoglobin and hemoglobin by excluding oxidants and proton donors from the immediate vicinity of the bound ligand. Leucine myoglobin Homo sapiens