Title : The binding site of NK receptors on HLA-C molecules.

Pub. Date : 1997 Mar

PMID : 9075934






1 Functional Relationships(s)
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1 Using site-directed mutagenesis, residues on HLA-C that determine the locus specificity (alphaVal-76), allotype group specificity (a dimorphism alphaAsn-80/Lys-80), and affinity of NKIR binding (a second pair of dimorphisms, alphaAla-73, Asp-90 or alphaThr-73, Ala-90) have been identified. Lysine major histocompatibility complex, class I, C Homo sapiens