Title : The organic component of diesel exhaust particles and phenanthrene, a major polyaromatic hydrocarbon constituent, enhances IgE production by IgE-secreting EBV-transformed human B cells in vitro.

Pub. Date : 1997 Feb

PMID : 9070347






3 Functional Relationships(s)
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Protein Name
Organism
1 DEP contain a wide spectrum of polycyclic aromatic hydrocarbons (PAH) that have been reported to have direct effects on the immune system, including the modulation of IgE production using various human and murine cell populations. Polycyclic Aromatic Hydrocarbons immunoglobulin heavy constant epsilon Homo sapiens
2 DEP contain a wide spectrum of polycyclic aromatic hydrocarbons (PAH) that have been reported to have direct effects on the immune system, including the modulation of IgE production using various human and murine cell populations. Polycyclic Aromatic Hydrocarbons immunoglobulin heavy constant epsilon Homo sapiens
3 We investigated the effects of the organic extract of DEP (PAH-DEP) and particularly, phenanthrene, a major component of DEP, in vitro on IgE production by 2C4/F3, a human Epstein-Barr virus transformed isotype switched, IgE producing B cell line. Polycyclic Aromatic Hydrocarbons immunoglobulin heavy constant epsilon Homo sapiens