Title : pH effects on the inhibition of extended-spectrum and classical TEM beta-lactamases by penicillanic acid sulphones.

Pub. Date : 1997 Jan

PMID : 9044033






1 Functional Relationships(s)
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1 MICs of piperacillin with tazobactam or sulbactam (4 mg/L) were higher at pH 6.5 than at pH 8.0 for Escherichia coli transconjugants with TEM-1 or TEM-2 enzymes, but not for those with TEM-3 or TEM-10 enzymes. Sulbactam hypothetical protein Escherichia coli