Title : Newly delivered transferrin iron and oxidative cell injury.

Pub. Date : 1997 Feb 17

PMID : 9042969






1 Functional Relationships(s)
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1 Cultured K562 cells, which maintain a stable cytosolic labile iron pool (LIP) of < 0.5 microM, underwent distinct changes after short exposures to transferrin (Tf) followed by t-butyl hydroperoxide (TBHP): (a) rise in LIP, detectable fluorimetrically; (b) increased lipid peroxidation and (c) eventual cell death. tert-Butylhydroperoxide transferrin Homo sapiens