Title : Natural killer cell receptors and MHC class I interactions.

Pub. Date : 1997 Feb

PMID : 9039769






1 Functional Relationships(s)
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1 Recent advances indicate that immunoreceptor tyrosine-based inhibitory motifs in the cytoplasmic domains of the killer cell inhibitory receptors and Ly-49 receptors recruit the SH2-containing protein tyrosine phosphatases, SHP-1 and SHP-2, resulting in inhibition of natural-killer- and T-cell-mediated cytotoxicity and cytokine secretion. Tyrosine protein tyrosine phosphatase non-receptor type 6 Homo sapiens