Pub. Date : 1997 Feb
PMID : 9029046
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of two UDP-glucuronosyltransferase isoforms sensitive to phenobarbital that are involved in morphine glucuronidation: production of isoform-selective antipeptide antibodies toward UGT1.1r and UGT2B1. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 2 | We document here in that two UDP-glucuronosyltransferase (UGT) isoforms sensitive to phenobarbital are involved in morphine glucuronidation in Wistar and Sprague-Dawley rats. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 3 | We document here in that two UDP-glucuronosyltransferase (UGT) isoforms sensitive to phenobarbital are involved in morphine glucuronidation in Wistar and Sprague-Dawley rats. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 4 | Although the morphine UGT activity in the liver of Gunn rats was increased by phenobarbital (PB) treatment, this was significantly less than that in the liver of PB-treated Wistar rats. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 5 | Although the morphine UGT activity in the liver of Gunn rats was increased by phenobarbital (PB) treatment, this was significantly less than that in the liver of PB-treated Wistar rats. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 6 | This study is the first demonstration that protein levels of two morphine UGT isoforms, UGT1.1r and UGT2B1, in the liver of Wistar and Sprague-Dawley rats are inducible by PB treatment. | Phenobarbital | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |