Title : Selective photoaffinity labeling of the inositol polyphosphate binding C2B domains of synaptotagmins.

Pub. Date : 1997 Feb 14

PMID : 9020139






3 Functional Relationships(s)
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1 Four photoaffinity analogues of IP3, IP4, and IP6 containing a P-1- or P-2-linked 4-benzoyldihydrocinnamidyl (BZDC) photophore were used to label glutathione S-transferase (GST) fusion constructs of the Syt II-C2A and C2B domains. Phytic Acid glutathione S-transferase kappa 1 Homo sapiens
2 Four photoaffinity analogues of IP3, IP4, and IP6 containing a P-1- or P-2-linked 4-benzoyldihydrocinnamidyl (BZDC) photophore were used to label glutathione S-transferase (GST) fusion constructs of the Syt II-C2A and C2B domains. Phytic Acid glutathione S-transferase kappa 1 Homo sapiens
3 The P-2-linked [3H]BZDC-IP6 showed efficient, IP6-displaceable labeling of the GST-Syt II-C2B. Phytic Acid glutathione S-transferase kappa 1 Homo sapiens