Pub. Date : 1997 Feb 14
PMID : 9020087
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase. | Lysine | CD38 molecule | Homo sapiens |
| 2 | Sequence analysis of the lysylendopeptidase-digested fragment of the labeled CD38 indicated that the FSBA-labeled residue was Lys-129. | Lysine | CD38 molecule | Homo sapiens |
| 3 | We introduced site-directed mutations to change the Lys-129 of CD38 to Ala and to Arg. | Lysine | CD38 molecule | Homo sapiens |
| 4 | These results indicate that Lys-129 of CD38 participates in cADPR binding and that ATP competes with cADPR for the binding site, resulting in the inhibition of the cADPR hydrolase activity of CD38. | Lysine | CD38 molecule | Homo sapiens |
| 5 | These results indicate that Lys-129 of CD38 participates in cADPR binding and that ATP competes with cADPR for the binding site, resulting in the inhibition of the cADPR hydrolase activity of CD38. | Lysine | CD38 molecule | Homo sapiens |