Title : LY295427, a novel hypocholesterolemic agent, enhances [3H]25-hydroxycholesterol binding to liver cytosolic proteins.

Pub. Date : 1996 Dec

PMID : 9017510






1 Functional Relationships(s)
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1 However, enhanced [3H]25-OH chol binding in the presence of LY295427 was evident in distinct fractions after immunodepletion of both the 90-100 kDa form of OSBP and a 170 kDa protein; and specific binding of a radioiodinated analog of LY295427 was detected in select fractions lacking [3H]25-OH chol binding in the absence of LY295427. LY 295427 LOW QUALITY PROTEIN: oxysterol-binding protein 1 Cricetulus griseus