Pub. Date : 1996 Dec 16
PMID : 9003780
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast. | Guanosine Triphosphate | Rho family GTPase CDC42 | Saccharomyces cerevisiae S288C |
| 2 | It is not clear how the activity of Ste20 is regulated in response to these different signals in vivo, but it has been demonstrated recently that binding of the small GTP binding protein Cdc42 is able to activate Ste20 in vitro. | Guanosine Triphosphate | Rho family GTPase CDC42 | Saccharomyces cerevisiae S288C |
| 3 | Here we show that Ste20 functionally interacts with Cdc42 in a GTP-dependent manner in vivo: Ste20 mutants that can no longer bind Cdc42 were unable to restore growth of ste20 cla4 mutant cells. | Guanosine Triphosphate | Rho family GTPase CDC42 | Saccharomyces cerevisiae S288C |