Pub. Date : 1997 Jan
PMID : 8996218
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine, the prototypical agonist for neuronal nicotinic acetylcholine receptors (NAChR), nonselectively activates NAChR limiting its use in elucidating the function of NAChR subtypes. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 2 | Nicotine, the prototypical agonist for neuronal nicotinic acetylcholine receptors (NAChR), nonselectively activates NAChR limiting its use in elucidating the function of NAChR subtypes. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 3 | Nicotine, the prototypical agonist for neuronal nicotinic acetylcholine receptors (NAChR), nonselectively activates NAChR limiting its use in elucidating the function of NAChR subtypes. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 4 | Nicotine, the prototypical agonist for neuronal nicotinic acetylcholine receptors (NAChR), nonselectively activates NAChR limiting its use in elucidating the function of NAChR subtypes. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |
| 5 | SIB-1765F is a subtype selective NAChR agonist that displaces [3H]-nicotine binding with an IC50 of 4.6 nM and [3H]-cytisine binding with an IC50 of 12.2 nM which is 2000- to 6000-fold lower than its displacement of [3H]-QNB or [125I]-alpha-bungarotoxin. | Nicotine | cholinergic receptor nicotinic beta 1 subunit | Rattus norvegicus |