Title : Ran-binding protein 1 (RanBP1) forms a ternary complex with Ran and karyopherin beta and reduces Ran GTPase-activating protein (RanGAP) inhibition by karyopherin beta.

Pub. Date : 1997 Jan 3

PMID : 8995296






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 RanBP1 is a cytosolic Ran-binding protein that inhibits RCC1-stimulated release of GTP from Ran. Guanosine Triphosphate RAN binding protein 1 Homo sapiens
2 These results demonstrate that RanBP1 and karyopherin beta interact with distinct sites of Ran and suggest that RanBP1 plays an essential role in nuclear transport by permitting RanGAP-mediated hydrolysis of GTP on Ran complexed to karyopherin beta. Guanosine Triphosphate RAN binding protein 1 Homo sapiens
3 These results demonstrate that RanBP1 and karyopherin beta interact with distinct sites of Ran and suggest that RanBP1 plays an essential role in nuclear transport by permitting RanGAP-mediated hydrolysis of GTP on Ran complexed to karyopherin beta. Guanosine Triphosphate RAN binding protein 1 Homo sapiens