Title : A test for neutrality of mutations of the lacZ transgene.

Pub. Date : 1996

PMID : 8991058






1 Functional Relationships(s)
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1 We have found that, after an acute dose of ethylnitrosourea (ENU, 250 mg/kg) the mutant frequency for both lacZ transgene and Dlb-1 remained constant between 10 and 70 days after mutagenesis in the small intestine, where cell turnover is rapid (approximately 7 days). Ethylnitrosourea beta-1,4-N-acetyl-galactosaminyl transferase 2 Mus musculus