Pub. Date : 1996 Jun
PMID : 8964835
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We measured the effects of PGF2 alpha and fluprostenol, a selective PGF2 alpha receptor (FP receptor) agonist, on phospholipase C(PLC) activation, on changes in the intracellular free calcium concentration ([Ca2+]i), and on protein tyrosine phosphorylation. | fluprostenol | heparan sulfate proteoglycan 2 | Homo sapiens |
| 2 | PGF2 alpha and fluprostenol activated PLC (determined by measuring the formation of inositol phosphates) and increased [Ca2+]i in a concentration-dependent manner. | fluprostenol | heparan sulfate proteoglycan 2 | Homo sapiens |
| 3 | The apparent affinity of the FP receptor for fluprostenol was higher than that for PGF2 alpha when measuring PLC activation, but the receptor displayed similar affinities for both agonists when measuring increases in [Ca2+]i. | fluprostenol | heparan sulfate proteoglycan 2 | Homo sapiens |
| 4 | These data suggest that fluprostenol and oxytocin activate PLC-beta rather than PLC-gamma isoforms. | fluprostenol | heparan sulfate proteoglycan 2 | Homo sapiens |
| 5 | These data suggest that fluprostenol and oxytocin activate PLC-beta rather than PLC-gamma isoforms. | fluprostenol | heparan sulfate proteoglycan 2 | Homo sapiens |